Women who are over 35 years old and smoke should not use seasonique. Cigarette smoking increases the risk of serious cardiovascular events from combination oral contraceptive (coc). Women who are over 35 years old and smoke should not use seasonique. Cigarette smoking increases the risk of serious cardiovascular events from combination oral contraceptive (coc). For postpartum women who are not breastfeeding, start seasonique no earlier than four to six weeks postpartum due to increased risk of thromboembolism.
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